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A CASE OF STEROID CELL TUMOR OF OVARY- CASE REPORT AND LITERATURE REVIEW

PREM ANAND A

Abstract


OBJECTIVE - Ovarian Steroidal Cell Tumor (NOS) not           otherwise specified are rare sex cord stromal tumors of ovary with malignant potential. These tumors arise in ovary and produce signs of virilization. Here we report a case of  peri-menopausal female with obstructed para-umbilical hernia with signs of virilization and yellowish orange tumor was found in left ovary. METHOD - Case report and review of medical literature . CASE REPORT - A 43 year old  peri-menopausal women was admitted with abdominal          distension and signs of intestinal obstruction due to  irreducible paraumbilical hernia. Patient was evaluated and taken up for emergency laparotomy for intestinal obstruction. Intraoperatively a segment of transverse colon with greater omentum was found inside the para-umbilical hernia sac and 1.5 litre of serous ascitic fluid was aspirated. Then thorough laparotomy was done and rest of bowel was found to be    normal. Ovaries were examined as patient had signs of    virilization and left ovary was enlarged 6cmx5cm in size and yellowish orange in colour with irregular surface, right ovary appeared to be normal. Bilateral oophorectomy was done. Virilization features decreased postoperatively.  CONCLUSION - Ovarian steroidal cell tumors are rare and very few cases has been reported worldwide. It is a type of sex cord stromal tumor. It can be benign as well as malignant.

 


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References


Scully RE atlas of tumor pathology.2nd ed.Washington,DC :Armed forces institute of

pathology:1979.tumors or the ovary and maldeveloped gonads,fallopian tube and broad ligament,pp.215-220

Hayes MC ScullyRE, ovarian steroid cell tumors(NOS) Am J surg pathology.1987:835-845

Hartman LC young RH, Evans MP, Podratz KC. ovarian sex cord –stromal tumor.In Hoskins WJ,editors principles and practise of gynaecologic oncology,2nd edition Philadelphia:lipincott raven:1997 pp1015-1019

Tayler HB ,NorrisHJ. Lipoid cell tumor of ovary.cancer:1967:201953-1962

Brewer CA,Shelvin D,Encouraging response ot steroidal cell tumor to GnRH agonist .obstet Gynaecology.1998:92.pp 661-663

Anderson PW,d”ablaing G,3rd,penny R,Sherrod A, Do YS,secreting of prorenin by virilising ovarian tumor. Gynaec oncol.1992:45;58-61

Flynn A, Ravindranath S: Steroid cell tumor, NOS, of ovary. Indian J Pathol Microbiol 2008, 51:461.

Liu AX, Sun J, Shao WQ, Jin HM, Song WQ: Steroid cell tumors, not otherwise specified (NOS), in an accessory ovary: a case report and literature review.Gynecol Oncol 2005, 97:260-262.

Deavers MT, Malpica A, Ordonez NG, Silva EG: Ovarian steroid cell tumors: an immunohistochemical study including a comparison of calretinin with inhibin.Int J Gynecol Pathol 2003, 22:162-167.

Bas F, Saka N, Darendeliler F, Tuzlali S, Ilhan R, Bundak R, Gunoz H: Bilateral ovarian steroid cell tumor in congenital adrenal hyperplasia due to classic 11beta-hydroxylase deficiency.J Pediatr Endocrinol Metab 2000, 13:663-667.

Outwater EK, Wagner BJ, Mannion C, McLarney JK, Kim B: Sex cord-stromal and steroid cell tumors of the ovary.Radiographics 1998, 18:1523-1546.

Zhao C, Vinh TN, McManus K, Dabbs D, Barner R, Vang R: Identification of the most sensitive and robust immunohistochemical markers in different categories of ovarian sex cord-stromal tumors.Am J Surg Pathol 2009, 33:354-366.

Reedy MB, Richards WE, Ueland F, Uy K, Lee EY, Bryant C, van Nagell JR Jr: Ovarian steroid cell tumors, not otherwise specified: a case report and literature review.Gynecol Oncol 1999, 75:293- 297.

Powell JL, , Dulaney DP, & Shiro BC 2005 Androgen-secreting steroid cell tumor of the ovary. South Medical Journal . 93: 1201–1204.

Karlan BY, , Markman MA, & Eifel PJ Sex-cord stromal tumors. DeVita V-TJr, , Hellman S, & Rosenberg S-A Cancer: Principles and Practice of Oncology . Lippincott Williams & Wilkinson Philadelphia 1392–1393.

Boyraz G, , Selcuk I, , Yusifli Z, , Usubutun A, & Gunalp S 2013 Steroid cell tumor of the ovary in an adolescent: a rare case report. Case Reports in Medicine . 2013: 527698. doi:10.1155/2013/527698)


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