
A case of giant upper abdominal mass
Abstract
Gastrointestinal stromal tumours (GISTs) are defined as gastrointestinal mesenchymal tumours expressing a protooncogene protein called CD117 detected by immunohistochemistry. GISTs are rare and constitute about 1-3 percent of all gastrointestinal (GI) malignancies, nevertheless they are the commonest type of GI mesenchymal tumours. We present a case of huge upper abdominal mass which radiologically showed an exophytic mass arsing from the left lobe of liver and spleen and was preoperatively diagnosed as a case of Hepatocellular carcinoma of left lobe of liver and Splenic hemangioma . Peroperatively we found a mass arising from stomach extending upto and adherent to splenic hilum and left dome of diaphragm, and we proceeded to do sleeve gastrectomy with enbloc resection of tumour and splenectomy. HPE report came as Malignant GASTRO INTESTINAL STROMAL tumour. Postoperative period was uneventful and patient was discharged. Surgery is the definitve cure for GIST. IMATINIB is now consider as drug of choice for metastatic and inoperable GIST
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Mazur MT, Clark HB. Gastric stromal tumors: Reappraisal of histogenesis. Am J Surg Pathol 1983; 7: 507–519.
Hirota S, Isozaki K, Moriyama Y et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science 1998; 279: 577–580.
Joensuu H, Roberts P, Sarlomo-Rikala M et al. Effect of the tyrosine kinase inhibitor STI571 in a patient with metastatic gastrointestinal stromal tumor. N Engl J Med 2001; 344: 1052–1056.
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