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Familial Adenomatous Polyposis is a rare disease of the colon, which presents with hundreds of polyps althrough the colon. The disease occurs as a result of various mutations in specific genes and is transmitted in an           autosomal dominant fashion in the families. There are many extra intestinal malignancies and manifestations associated with the disease, and many related syndromes which all could predispose to malignancy, not only in the colon but in many other body parts even brain. Screening of the family               members, and early colectomy for those who show signs of the disease could prevent early mortality due to the colonic manifestations of the disease. Here we present a case of Familial Adenomatous Polyposis with growths in ascending colon and hepatic flexure which was successfully treated with Total procto colectomy and Brookes end ileostomy.


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