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A rare case of sertoli leydig cell tumour with successful pregnancy following oophorectomy



Ovarian SLCT are rare sex cord stromal tumours accounting for 0.1 percent of ovarian tumours. Characteristic feature of this tumour is virilisation due to testosterone  secretion by Leydig cells.50 percent of patients have no endocrine manifestations. Most of the tumours are benign and unilateral with favourable prognosis following conservative surgery. One such is this case report of intermediate type SLCT in a woman who presented with virilising features and secondary amenorrhoea and underwent unilateral    salphingo-oophorectomy. Post surgery she resumed regular cycles and had spontaneous conception 8 months later with successful pregnancy and good neonatal outcome.


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Young RH, Scully RE. Ovarian Sertoli-Leydig cell tumours. A clinicopathological analysis of 207 cases. Am J Surg Pathol. 1985;9:543–569.

Lantzsch T, Stoerer S, Lawrenz K, Buchmann J, Strauss H-G, Koelbl H. Sertoli-Leydig cell tumour. Arch Gynecol Obstet. 2001;264:206–208.

Zaloudek C, Norris H. Sertoli-Leydig cell tumors of the ovary. A clinicopathological study of 64 intermediate and poorly differentiated neoplasms. Am J Surg Pathol. 1984;8:405–418.

Sood AK, Gershenson DM. Management of early-stage ovarian cancer. In: Bristow RE, Karlan BY, editors. Surgery for Ovarian Cancer: Principles and Practice. London, UK: Taylor and Francis; 2005. pp. 57–86.

Gershenson DM, Copeland LJ, Kavanagh JJ, et al. Treatment of metastatic tumour of the ovary with cisplastin, doxorubicin and cyclophosphamide. Obstet Gynecol. 1987;70:765–769.


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