Cover Image




We report the case of young primiparous women with Transient ischemic attack diagnosed as Primary  antiphospholipid antibody syndrome. Lupus anticoagulant and anticardiolipin antibodies were elevated. There was no clinical or laboratory evidence for other autoimmune or systemic illnesses. We are presenting the case due to the rarity of the same.


Full Text:



Jerrold SL, Branch DW, Rauch. The antiphospholipid syndrome. N Engl J Med 2002; 346:752-62.

Ameri A, Bousser M. Cerebral venous thrombosis. Neurol Clin 1992; 10:87-111.

Barry L Myons, Deborah Mccurdy. APLA syndrome, eMedicine update, Sept. 4, 2002.

Moodiey J, Bhoola V, Duursma J, et al. The association of antiphospholipid antibodies with severe early onset preeclampsia. S Afr Med J. 1995; 85:105-107.

Meyer, O. (2003) Lupus et autres connectivites et vie hormonale. Gynécologie Obstétrique & Fertilité, 31, 746- 756. Doi: 10.1016/S1297-9589(03)00203-0

Carbonne, B. and Lejeune, V. (2003) Modalités thérapeutiques d’une maladie abortive d’origine dysimmunitaire. Gynécologie Obstétrique & Fertilité, 31, 789-793. Doi: 10.1016/S1297- 9589(03)00210-8

Arvieux, J. and Hachulla, E. (2002) Le syndrome des antiphospholipides. Annales de Cardiologie et d Angé- iologie, 51, 146-151. doi:10.1016/S0003-3928(02)00087-2

Firkin, B.G., Howard, M.A. and Radford, N. (1980) possible relationship between lupus inhibitor and recurrent abortion in young women. Lancet, 2, 366. Doi: 10.1016/S0140-6736(80)90361

Lejeune, V. (2006) Fausses couches spontanées précoces répétées: Quelleprise encharge proposer en 2006? Gyné- cologie Obstétrique & Fertilité, 34, 927-993. doi:10.1016/j.gyobfe.2006.08.008

Nielsen, H.S. and Christiansen, O.B. (2005) Prognostic impact of anticardiolipin antibodies in women

with recurrent miscarriage negative for the lupus anticoagulant. Human Reproduction, 20, 1720-1728. doi:10.1093/humrep/deh79.

Wilson, W.A., Gharavi, A.E. and Koike, T. (1999) International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome. Arthritis & Rheumatism, 42, 1309-1311. Doi: 10.1002/1529-0131(199907)42:73.0.CO; 2-F

De Maistre, E. (2003) Anticorps dits antiphospholipides et troubles de la reproduction: Les données biologiques. Gynécologie Obstétrique & Fertilité, 31, 794-796. Doi: 10.1016/S1297- 9589(03)00207-8

Branch, D.W., Peaceman, A.M., Druzin, M., et al. (2000) Multicenter, placebo-controlled pilot study of intravenous immune globulin treatment of antiphospholipid syndrome during pregnancy. The Pregnancy Loss Study Group. American Journal of Obstetrics & Gynecology, 122-182. doi:10.1016/S0002-9378(00)70500-X


  • There are currently no refbacks.

Creative Commons License
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.

An Initiative of The Tamil Nadu Dr MGR Medical University