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A rare complication of hyperemesis during pregnancy-Wernicke's encephalopathy

Hajira Faphima S .

Abstract


Wernicke's encephalopathy is a potentially reversible yet serious neurological manifestation caused by vitamin B1 (thiamine) deficiency. It is usually suspected in the setting of chronic alcoholism and might not be recognized when associated with other conditions. We describe a young primigravida presenting with hyperemesis gravidarum and altered sensorium. Characteristic brain MRI findings and rapid response to thiamine suggested that she had Wernicke's encephalopathy, possibly due to excessive vomiting and dextrose administration without thiamine supplementation. A high index of suspicion is required, since delayed or lack of treatment may lead to high morbidity and mortality.

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