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Malignant peripheral nerve sheath tumour of the cervical symphathetic chain

Guhan V .

Abstract


Malignant peripheral nerve sheath tumors (MPNSTs) are sarcomas which originate from peripheral nerves or from cells of the nerve sheath, such as Schwann cells, perineural cells, or fibroblasts. Upto 50 of MPNSTs occur in patients with NF1 demonstrating the tendency to arise from a preexisting neurofibroma. A case of left cervical symphatetic MPNST in an individual with neurofibromatosis presenting with Horner's syndrome was treated sucessfully by surgical excision and adjuvant radiation.


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