Nevus comedonicus: a case series and review of literature
Abstract
Nevus comedonicus (NC) is a rare nevus of
epithelial origin centered on the pilosebaceous unit,
estimated to be present in 1: 45,000–1: 100,000 births. In
50% of cases, the condition develops immediately after birth
and appears in infancy as a linear shiny patch with
development of comedones early in life. It is characterized
by closely grouped dilated follicular openings with horny
plugs that mimic comedones. Extra cutaneous
manifestations have also been reported in individuals with
NC, leading to the diagnosis of nevus comedonicus
syndrome (NCS) which can feature NC lesions, ipsilateral
cataracts, and neurological and skeletal abnormalities. We
present our experience with this disease, describing the
cases encountered and treatment provided. Also provided is
a detailed review of literature on this rare condition.
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