Cover Image

Interesting Case of Iris Depigmentation

Vinitha L Rashme AND Rathinam S R .

Abstract


36-year-old male presented with complaints of     sudden loss of vision in both eyes for 2 days. Five days    earlier he was treated with oral antibiotics for fever. His visual acuity in both eyes was perception of light with accurate  projection of rays. Slit lamp examination showed diffuse   congestion with corneal edema and severe pigment         dispersion on the cornea and raised digital tension. B scan showed normal posterior segment. UBM revealed medial    and temporal iris cysts. His previous reports revealed history of taking oral moxifloxacin for fever. So this is a case of    acute iris depigmentation following systemic moxifloxacin. Patient was started on inj. Dexamethasone, oral  Prednisolone, topical steroids and anti glaucoma medications. At follow up his  visual acuity were 6/6 in both eyes with clear cornea and iris atrophy. We are reporting this case for its rarity and to  increase awareness of this adverse effect of moxifloxacin.


Full Text:

PDF

References


WefersBettink-Remeijer M, Brouwers K, van Langenhove L, De Waard PW, Missotten TO, Martinez Ciriano JP et al. Uveitis-like syndrome and iris transillumination after the use of oral moxioxacin. Eye 2009; 23: 2260–2262.

Willermain F, Deflorenne C, Bouffioux C, Janssens X, Koch P, Caspers L. Uveitis-like syndrome and iris transillumination after the use of oral moxifloxacin. Eye (Lond). 2010;24(8):1419.

Tugal-tutkun I, Urgancioglu M. Bilateral acute depigmentation of the iris. GraefesArch ClinExpOphthalmol. 2006;244(6):742-6.

Hinkle, D. M., Dacey, M. S., Mandelcorn, E., Kalyani, P., Mauro, J., Bates, J. H., ... & Davis, J. L. (2012). Bilateral uveitis associated with fluoroquinolone therapy. Cutaneous and ocular toxicology, 31(2), 111-116.


Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.

An Initiative of The Tamil Nadu Dr MGR Medical University