A RARE CASE REPORT GASTRO INTESTINAL STROMAL TUMOR ( GIST ) IN A JEJUNAL DIVERTICULUM
Abstract
Introduction Jejunal diverticulosis is an
uncommon condition and its association
with gastrointestinal stromal tumor
(GIST) is very rare. We report a rare
case of GIST arising in a jejunal diverticulm
presenting as a pelvic mass.Case
report A fifty year old lady presented with
a mass in the right lower abdomen associated
with pain, vomiting and loss of
weight. Computerised tomography of the
abdomen showed a large, heterogenous
mass arising from the right ovary. At
laparotomy, however, she was found to
have a large lobulated tumor arising from
the jejunum which was resected. The
mucosal surface of the resected jejunum
showed the mouth of the diverticulm harbouring
the tumor. Histopathology was
suggestive of high grade GIST which
was confirmed by immunohistochemistry.
Patient was started on Tab. Imatinib 400
mgday. Conclusion Abdominal cavity
continued to be a pandoras box and
despite improvised imaging studies like
computerized tomography, laparotomy is
the final answer in clinching the diagnosis.
Gastrointestinal stromal tumor( GIST) in a
true jejunal diverticula is extremely rare
and can be confirmed by immunohistochemistry.
Full Text:
PDFReferences
L. P. Anderson, B. Schjoldager, B.Halver.
Jejunal diverticulosis in a family. Scand J
Gastroenterology 1988; 23: 672-674.
W. T. Cooke, E. V. Cox, D.J. Fone,
M.J.Meynell, R. Gaddie. The clinical and
metabolic significance of Jejunal diverticula.
Gut 1963;4:115.
Neil J. McC, Mortensen , Shazad
Ashraf. The small and large intestine
in: Bailey and Love short practice of
surgery 25th ed:2008; 1157-1158.
A. Sadaf, D. Sunil, B. Athar, B.
Khalid. Obscure Gastrointestinal
Bleed from a Gastrointestinal Stromal
Tumor in a Jejunal Diverticulum: A
case report. Case Rep Oncol
;3:19–23.
S. Schepers, R. Vanwyck. Small
bowel gastrointestinal stromal tumor
( GIST) arising in a jejunal diverticulum.
JBR–BTR 2009; 92: 23-24.
K Chandramohan, Mudit Agarwal,
Gopal Gurjar, Rohan C Gatti,
Mahesh H Patel, Preeti Trivedi etal.
Gastrointestinal stromal tumour in
Meckel's diverticulum. World Journal
of Surgical Oncology 2007;5:50.
Monica M.Bertgnolli. Gastrointestinal
stromal tumors In Maingot’s abdominal
operations 11th ed:2007;439
-454
Liegl, Bernadette, Hornick, Jason
L, Corless, Christopher L, Fletcher,
Christopher. Monoclonal Antibody
DOG1.1 Shows Higher Sensitivity
Than KIT in the Diagnosis of Gastrointestinal
Stromal Tumors, Including
Unusual Subtypes. American Journal
of Surgical Pathology.March
:33 ; Issue 3 - pp 437-446
Christopher Kosmidis, Christopher
Efthimiadis, Sofia Levva, George
Anthimidis, Sofia Baka, Marios Grigoriou
etal. Synchronous colorectal
adenocarcinoma and gastrointestinalstromal
tumor in Meckel's
Refbacks
- There are currently no refbacks.
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.
An Initiative of The Tamil Nadu Dr MGR Medical University